Ethyl (2S)-2-hydroxypropanoate(CAS: 687-47-8)

Ethyl (2S)-2-hydroxypropanoate (CAS: 687-47-8) is a colorless liquid with a melting point of -45°C to -43°C, boiling point of 103°C to 105°C, and a molecular weight of approximately 128.15 g/mol. It has a high solubility in water and organic solvents. Chemically, it is mildly acidic and can react with bases and nucleophiles. It is not particularly reactive under normal conditions but can undergo hydrolysis under acidic or basic conditions.

Ethyl (2S)-2-hydroxypropanoate (CAS: 687-47-8) can be synthesized via esterification of lactic acid with ethanol in the presence of an acid catalyst like sulfuric acid. The reaction is typically carried out at elevated temperatures, and the product can be purified by recrystallization or distillation. The yield is generally high, around 90%, and the process is selective, producing the desired (2S)-isomer.

Ethyl (2S)-2-hydroxypropanoate (CAS: 687-47-8) is used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry to modify polymer properties and in the production of sensors due to its reactivity. Additionally, it plays a role in semiconductor manufacturing as a solvent and in the coatings industry as a component in formulation.

When handling Ethyl (2S)-2-hydroxypropanoate (CAS: 687-47-8), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, well-ventilated area and away from incompatible materials like strong oxidizers and bases. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.