3-Bromo-2,6-dimethylpyridine(CAS: 3430-31-7)

3-Bromo-2,6-dimethylpyridine is a crystalline compound with a molecular weight of approximately 217.04 g/mol. Its solubility in water is low, with a maximum of around 0.1 g/L. It is relatively stable but can react with strong bases to form pyridine derivatives. This compound has a pKa of about 5.3 and is slightly acidic.

3-Bromo-2,6-dimethylpyridine is typically synthesized via the bromination of 2,6-dimethylpyridine using N-bromosuccinimide (NBS) or bromine in the presence of a suitable Lewis acid like aluminum bromide (AlBr₃). The process yields the compound with a high degree of selectivity and good yield.

3-Bromo-2,6-dimethylpyridine is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for the development of specific polymer additives. Additionally, it has applications in the semiconductor industry for the production of organic semiconductors and in sensors for its unique reactivity.

When handling 3-Bromo-2,6-dimethylpyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using an appropriate absorbent, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.