5-O-Methylgenistein(CAS: 4569-98-6)

5-O-Methylgenistein is a yellow to orange crystalline solid with a molecular weight of approximately 406.44 g/mol. It is slightly soluble in methanol and dimethylformamide (DMF) but is only sparingly soluble in water. This compound is known to be stable under normal conditions but exhibits reactivity towards strong acids and bases. It is used in various assays due to its chemical stability and reactivity.

5-O-Methylgenistein is typically synthesized through a series of reactions involving genistein as the starting material. The process involves methylation followed by acetylation. Commonly used catalysts include sulfuric acid, and the reaction yields 5-O-methylgenistein with good selectivity and yield, making it a reliable method for large-scale production.

5-O-Methylgenistein finds applications in the pharmaceutical industry for its anti-estrogenic properties, making it useful in hormone-related drugs. It is also used in the food industry as a potential natural pigment. Additionally, it has applications in the cosmetic industry for its antioxidant effects and in the research of biosensors for its unique chemical properties.

When handling 5-O-Methylgenistein, it is important to work in a well-ventilated area or a fume hood due to its potential for inhalation hazards. PPE such as gloves, lab coats, and safety goggles should be worn to protect against skin contact and eye irritation. Spills should be cleaned up using appropriate methods, and the Material Safety Data Sheet (MSDS) should be consulted for specific safety guidelines.