4,6-Dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine(CAS: 98141-42-5)

4,6-Dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine is a white crystalline solid with a molecular weight of approximately 222.03 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and DMSO. The compound is known for its high reactivity, particularly in nucleophilic substitution reactions.

4,6-Dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine is typically synthesized via a multistep process involving the reaction of chloroacetyl chloride with 1-methyl-4-chloropyrazole. The reaction is catalyzed by a suitable acid or base, and it proceeds with good selectivity to yield the target compound in moderate to high yield.

4,6-Dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine is primarily used in pharmaceuticals and as an intermediate in the synthesis of various drug candidates. It is also utilized in the development of sensors and as a reagent in organic chemistry research.

When handling 4,6-Dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using an appropriate absorbent material, and the area should be thoroughly washed down. Consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.