3-Bromo-2-fluorobenzaldehyde(CAS: 149947-15-9)

3-Bromo-2-fluorobenzaldehyde (CAS: 149947-15-9) is a crystalline solid with a molecular weight of approximately 217.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles, and undergoes electrophilic aromatic substitution reactions readily.

3-Bromo-2-fluorobenzaldehyde can be synthesized by the reaction of 2-fluorobenzaldehyde with N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. This method provides good yields and high selectivity, making it a common approach for the preparation of this compound.

3-Bromo-2-fluorobenzaldehyde (CAS: 149947-15-9) is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It also finds applications in the production of polymers and as a reagent in analytical chemistry and material science due to its reactive nature.

When handling 3-Bromo-2-fluorobenzaldehyde (CAS: 149947-15-9), it is essential to wear proper personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be carefully cleaned up using appropriate procedures, and the Material Safety Data Sheet (MSDS) should be consulted for detailed spill and disposal instructions.