6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone(CAS: 135631-90-2)

6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone is a crystalline solid with a molecular weight of approximately 246.04 g/mol. It has a high solubility in organic solvents like DMSO and acetonitrile but is sparingly soluble in water. The compound is known for its low reactivity under normal conditions, but it can undergo substitution reactions in the presence of strong bases or reducing agents.

6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone can be synthesized via a multistep process involving bromination of 4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone. This typically involves the use of N-bromosuccinimide (NBS) as a brominating agent in the presence of a suitable solvent like dichloromethane. The reaction is carried out under UV light to enhance the reactivity and yield is usually around 70-80%.

6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the polymer industry for the development of specialty polymers, and in the semiconductor industry for the fabrication of organic thin-film transistors and sensors.

When handling 6-Bromo-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. In case of a spill, use appropriate spill clean-up kits and ensure proper disposal. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.