Indoline-4-carbonitrile(CAS: 885278-80-8)

Indoline-4-carbonitrile (CAS: 885278-80-8) is a colorless crystalline solid with a molecular weight of approximately 164.14 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. Indoline-4-carbonitrile exhibits moderate reactivity, particularly towards nucleophilic substitution and electrophilic addition reactions.

Indoline-4-carbonitrile can be synthesized via the reaction of indoline-4-carbonitrile with a strong base, such as potassium tert-butoxide, in an organic solvent like THF or DCM. The reaction is typically carried out at room temperature with good selectivity and yield.

Indoline-4-carbonitrile (CAS: 885278-80-8) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds and intermediates. It also finds applications in the polymer industry as a precursor for the production of certain polymers. Additionally, it is used in the development of sensors and semiconductors.

When handling Indoline-4-carbonitrile (CAS: 885278-80-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from direct sunlight and incompatible materials. In case of spillage, handle it according to the Safety Data Sheet (SDS) guidelines, and dispose of it safely in accordance with local regulations.