(3aS,8bS)-7-Bromo-3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid(CAS: 88277-50-3)

(3aS,8bS)-7-Bromo-3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid is a crystalline solid with a molecular weight of approximately 255.03 g/mol. It exhibits low water solubility and is less reactive in non-polar solvents. This compound is stable under normal conditions but can degrade under strong acid or base conditions. It has a melting point of around 225-228°C.

(3aS,8bS)-7-Bromo-3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid can be synthesized through a bromination reaction on the 5-position of 3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid. This process often uses N-bromosuccinimide (NBS) as the brominating agent. The yield is typically around 80%, and the reaction proceeds with high selectivity.

(3aS,8bS)-7-Bromo-3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid is used in pharmaceuticals for developing new drug candidates due to its unique chemical structure. It is also utilized in the synthesis of organic semiconductors and as a functional material in sensor technology.

When handling (3aS,8bS)-7-Bromo-3a,8b-dihydro-3H-benzo[b]cyclopenta[d]furan-5-carboxylic acid, wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to minimize exposure. Keep the material away from strong acids and bases to prevent degradation. In case of a spill, use appropriate cleanup materials and dispose of contaminated materials according to safety data sheet (SDS) guidelines.