1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde(CAS: 728034-12-6)

1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde is a crystalline solid with a molecular weight of approximately 165.15 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is known for its aromatic and aldehydic reactivity, making it suitable for various synthetic reactions.

1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde can be synthesized through the condensation of 1H-pyrrolo[2,3-b]pyridine with formaldehyde in the presence of a suitable catalyst such as p-toluenesulfonic acid. The reaction yields a product with high selectivity and good yield, typically around 70-80%.

1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde is used in the pharmaceutical and chemical industries for the synthesis of complex organic molecules. It is also relevant in the development of polymers and sensors, where its unique chemical properties contribute to the functionality of these materials.

When handling 1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Store it in a well-ventilated area and avoid contact with skin and eyes. In case of a spill, clean it up using appropriate PPE and refer to the Material Safety Data Sheet (MSDS) for specific instructions.