Recent advances in the synthesis and reactivity of quinoxaline

Literature Information

Publication Date 2021-03-10
DOI 10.1039/D0QO01575J
Impact Factor 5.281
Authors

Gauravi Yashwantrao, Satyajit Saha


View Original

Abstract

Quinoxaline has become a subject of extensive research due to its emergence as an important chemical moiety, demonstrating a wide range of physicochemical and biological activities. The last few decades have witnessed several publications utilizing quinoxaline scaffolds for the design and development of numerous bioactive molecules, dyes, fluorescent materials, electroluminescent materials and organic sensitizers for solar cell applications and polymeric optoelectronic materials. Therefore, to fulfill the need of the scientific community, tremendous effort has been observed in the development of newer synthetic strategies as well as novel methodologies to decorate the quinoxaline scaffold with proper functional groups. Hence, to provide an updated comprehensive account of the diverse synthetic routes to access quinoxaline as well as approaches for structural diversifications, we have attempted to document the synthetic strategies and their functionalization with possible mechanistic rationalization. This will no doubt be helpful for the readers who are anticipating a comprehensive overview on quinoxaline as well as benefitting researchers for future development.

Related Literature

Stereochemistry of hydrogen removal from the ‘unactivated’ C-3 position of 4-hydroxybutyryl-CoA catalysed by 4-hydroxybutyryl-CoA dehydratase

Richard Scott, Ulrike Näser, Peter Friedrich, Thorsten Selmer, Wolfgang Buckel, Bernard T. Golding

2004-04-23 Communication

DOI: 10.1039/B402322F

Synthesis and study of a new diamidodipyrromethane macrocycle. An anion receptor with a high sulfate-to-nitrate binding selectivity

Jonathan L. Sessler, G. Dan Pantos, Yuri A. Ustynyuk

2004-05-03 Communication

DOI: 10.1039/B403665D

Synthesis and unprecedented oxidation of a cationic Sb-analogue of an Arduengo's carbene

Dietrich Gudat, Timo Gans-Eichler, Martin Nieger

2004-09-22 Communication

DOI: 10.1039/B409657F

Step-wise dis-assembly of trimesic acid: mono- and bis(methanol) solvates

Sophie H. Dale, Mark R. J. Elsegood, Simon J. Richards

2004-05-10 Communication

DOI: 10.1039/B402922D

Self-assembly of aluminium–salen coupled nanostructures from encoded modules with cleavable disulfide DNA-linkers

Raymond S. Brown, Morten Nielsen, Kurt V. Gothelf

2004-05-27 Communication

DOI: 10.1039/B403956D

Halide anion directed assembly of luminescent pseudorotaxanes

David Curiel, Paul D. Beer, Rowena L. Paul, Andrew Cowley, Mark R. Sambrook, Fridrich Szemes

2004-04-22 Communication

DOI: 10.1039/B401900H

A novel, stereoselective and convergent synthesis of aryltetralins

Steven M. Miles, Stephen P. Marsden, Robin J. Leatherbarrow, William J. Coates

2004-09-01 Communication

DOI: 10.1039/B409528F

Novel cobalt-free oxygen permeable membrane

Xuefeng Zhu, Haihui Wang, Weishen Yang

2004-04-08 Communication

DOI: 10.1039/B400857J

Ferromagnetic NiII–GdIII interactions in complexes with NiGd, NiGdNi, and NiGdGdNi cores supported by tripodal ligands

Tomoka Yamaguchi, Yukinari Sunatsuki, Masaaki Kojima, Haruo Akashi, Masanobu Tsuchimoto, Nazzareno Re, Shutaro Osa, Naohide Matsumoto

2004-04-05 Communication

DOI: 10.1039/B401033G

Silicon-assisted propargylic transfer to aldehydes

Kiew-Ching Lee, Man-Jing Lin, Teck-Peng Loh

2004-09-21 Communication

DOI: 10.1039/B411653D

You might also like

Compound Q&A

What precautions should be taken when handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3)?

When handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3), it is ...

71193-32-32-Chloro-1,2-bis(4-m...
Compound Q&A

What industries use 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride (CAS: 224789-26-8)?

4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl...

224789-26-84-Ethoxy-3-(5-methyl...
Compound Q&A

How should Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) be stored?

Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) should be stored in a c...

2681-55-2Methyl 3-Oxo-4-Andro...
Compound Q&A

What are the main uses of (R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (CAS: 909725-61-7)?

(R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid is primarily used i...

909725-61-7(R)-3-Amino-4-(3-hex...
Compound Q&A

What regulatory guidelines apply to 2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-3)?

2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-...

1254120-14-32-Methyl-2-propanyl ...
Compound Q&A

Are there alternatives to (E)-4-(tert-Butoxy)-4-oxobut-2-enoic acid (CAS: 135355-96-3) in synthesis?

There are alternative reagents that can be used in synthesis instead of (E)-4-(t...

135355-96-3(E)-4-(tert-Butoxy)-...
Compound Q&A

What are the physical and chemical properties of [2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8)?

[2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8) is a crystallin...

121202-20-8[2-(3-Chlorophenyl)-...
166249-17-8Methyl (2S)-[(4S)-2,...
Compound Q&A

What is the market or research trend for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0)?

The market for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0) is driven by its use...

42865-19-01-Bromo-2-isocyanato...
Compound Q&A

What are the main uses of 4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3)?

4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3) is primarily used in re...

147065-06-34-Nitro-D-phenylalan...

Source Journal

Organic Chemistry Frontiers

Organic Chemistry Frontiers
CiteScore: 7.8
Self-citation Rate: 8.7%
Articles per Year: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.