Sensing of citrulline modifications in histone peptides by deep cavitand hosts

Literature Information

Publication Date 2019-10-11
DOI 10.1039/C9CC07002H
Impact Factor 6.222
Authors

Adam D. Gill, Briana L. Hickey, Siwen Wang


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Abstract

Arrayed cavitand:fluorophore sensor complexes can selectively sense small citrulline modifications at arginine residues on post-translationally modified peptides. The sensor can differentiate between different numbers of citrulline modifications, and a simple two-fluorophore, 6-component array can effect cross-reactive discrimination between single modifications in aqueous solution.

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