AgNO3-catalyzed direct C–H arylation of quinolines by oxidative decarboxylation of aromatic carboxylic acids
Literature Information
Publication Date
2016-12-05
DOI
10.1039/C6QO00533K
Impact Factor
5.281
Authors
Jin-Wei Yuan, Liang-Ru Yang, Pu Mao, Ling-Bo Qu
View Original
Abstract
An efficient silver-catalyzed intermolecular decarboxylative arylation of quinolines has been developed using cheap aromatic carboxylic acids as arylating reagents under microwave irradiation. The reaction demonstrates a broad substrate scope and excellent functional group tolerance. This method provided an effective and easy way to synthesize arylated quinoline derivatives. The radical trapping experiments showed that this process involved the radical mechanism.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
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[3-(2,6-Dichlorophenyl)-5-isopropyl-1,2-oxazol-4-yl]methanol
CAS Number:
278597-30-1
Molecular Formula:
C13H13Cl2NO2
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