Highly efficient construction of large molecular cavity using 1,3-alternate tetraoxacalix[2]arene[2]triazine as a platform

Literature Information

Publication Date 2008-06-23
DOI 10.1039/B805293J
Impact Factor 6.222
Authors

Bao-Yong Hou, Qi-Yu Zheng, De-Xian Wang, Zhi-Tang Huang, Mei-Xiang Wang


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Abstract

In the presence of K2CO3 in refluxing THF, dichloro-substituted tetraoxacalix[2]arene[2]triazine, a readily available macrocyclic compound from cyanuric acid chloride and benzyl 1,3-dihydroxybenzoate, underwent highly efficient nucleophilic displacement reactions with bis-nucleophilic reagents of different geometry, length and chirality in a 2+2 fashion to produce large and size-tunable cavity bis-tetraoxacalix[2]arene[2]triazines in good to excellent yields.

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