Chemoselective derivatization of alkaloids in periwinkle

Literature Information

Publication Date 2007-07-11
DOI 10.1039/B708919H
Impact Factor 6.222
Authors

M. Carmen Galan, Elizabeth McCoy, Sarah E. O'Connor


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Abstract

The terpene indole alkaloidbiosynthetic pathway can utilize a secologanin substrate analog containing a handle for functionalization, and the resulting non-natural alkaloids can be chemoselectively derivatized in crude extracts of plant tissue.

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