Superparamagnetic γ-Fe2O3 nanoparticles with tailored functionality for protein separation
Literature Information
Mohammed Ibrahim Shukoor, Filipe Natalio, Muhammad Nawaz Tahir, Vadim Ksenofontov, Helen Annal Therese, Patrick Theato, Heinz C. Schröder, Werner E. G. Müller, Wolfgang Tremel
Polymer coated superparamagnetic γ-Fe2O3 nanoparticles were derivatized with a synthetic double-stranded RNA [poly(IC)], a known allosteric activator of the latent (2-5)A synthetase, to separate a single 35 kDa protein from a crude extract which cross reacted with antibodies raised against the sponge enzyme.
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