Cyclodextrin-based isolation of Ostwald's metastable polymorphs occurring during crystallization
Literature Information
Yoh Sonoda, Fumitoshi Hirayama, Hidetoshi Arima, Yoshihiro Yamaguchi, Wolfram Saenger, Kaneto Uekama
We describe a novel approach for the selective isolation of Ostwald's intermediate metastable polymorphs occurring during an early stage of crystallization, by utilizing the inclusion complex formed with a cyclic oligosaccharide derivative, 2,6-di-O-methyl-β-cyclodextrin.
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