Highly enantioselective dynamic kinetic resolution and desymmetrization processes by cyclocondensation of chiral aminoalcohols with racemic or prochiral δ-oxoacid derivatives
Literature Information
Mercedes Amat, Oriol Bassas, Miquel A. Pericàs, Mireia Pastó, Joan Bosch
Cyclocondensation reactions of aminoalcohols 7 and 8 with racemic or prochiral δ-oxoacid derivatives provide polysubstituted lactams with high enantioselectivity in a process that involves dynamic kinetic resolution and/or desymmetrization of enantiotopic or diastereotopic ester groups.
Related Literature
Atomic Spectrometry Update—Inorganic Mass Spectrometry and X-Ray Fluorescence Spectrometry
DOI: 10.1039/JA990050243R
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