Observation of high enantioselectivity for the gas phase hydrogenation of methyl pyruvate using supported Pt catalysts pre-modified with cinchonidine

Literature Information

Publication Date 2003-06-27
DOI 10.1039/B304976K
Impact Factor 6.222
Authors

Nicholas Dummer, David J. Willock, Stuart H. Taylor, Richard P. K. Wells, Peter B. Wells, Graham J. Hutchings


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Abstract

Pt supported on α-Al2O3, γ-Al2O3 and SiO2 pre-modified with cinchonidine gives over 50% ee in the hydrogenation of methyl pyruvate to methyl lactate using gas phase reactants at 40 °C giving the first clear observation of high enantioselection at the gas/solid interface.

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