Synthesis of a novel crown ether derived from chiro-inositol and its catalytic activity on the asymmetric Michael addition

Literature Information

Publication Date 2003-06-16
DOI 10.1039/B304649D
Impact Factor 6.222
Authors

Takahiko Akiyama, Mikiko Hara, Kohei Fuchibe, Shigeru Sakamoto, Kentaro Yamaguchi


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Abstract

A novel 18-membered chiral crown ether was prepared in four steps starting from L-quebrachitol, a chiro-inositol, and its catalytic activity in the Michael addition reaction of glycine imine with several Michael acceptors was studied.

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