A novel one-pot three-component tandem Michael/aldol/Horner–Wadsworth–Emmons (HWE) reaction of lithium alkylselenolates with 1-alkynylphosphine oxides and aldehydes: facile synthesis of selenium-substituted allenes

Literature Information

Publication Date 2003-06-11
DOI 10.1039/B304527G
Impact Factor 6.222
Authors

Zheng-Chang Xiong


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Abstract

The one-pot tandem Michael/aldol/Horner–Wadsworth–Emmons (HWE) reaction of lithium alkylselenolates, 1-alkynylphosphine oxides and aldehydes in THF provides a new general access to selenium-substituted allenes with good to excellent yields.

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