Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin

Literature Information

Publication Date 2003-05-23
DOI 10.1039/B304252A
Impact Factor 6.222
Authors

John L. Sorensen, John C. Vederas


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Abstract

A novel compound, monacolin N, has been isolated from fermentation cultures of Aspergillus nidulans in which the lovastatin polyketide synthase genes lovB and lovC are heterologously expressed.

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