Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin
Literature Information
John L. Sorensen, John C. Vederas
A novel compound, monacolin N, has been isolated from fermentation cultures of Aspergillus nidulans in which the lovastatin polyketide synthase genes lovB and lovC are heterologously expressed.
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DOI: 10.1039/D3CB00077J
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![4,4-Difluoro-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline structure 4,4-Difluoro-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline structure](https://static.chemtradehub.com/structs/119/1194032-23-9-f426.webp)
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