Regioselective hydroxylation of the xylyl linker in a diiron(iii) complex having a carboxylate-rich ligand with H2O2

Literature Information

Publication Date 2003-06-25
DOI 10.1039/B304171A
Impact Factor 6.222
Authors

Hideki Furutachi, Mizue Murayama, Amane Shiohara, Satoshi Yamazaki, Shuhei Fujinami, Akira Uehara, Masatatsu Suzuki, Seiji Ogo, Yoshihito Watanabe, Yonezo Maeda


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Abstract

Reaction of a diiron(III) complex having a xylta4− ligand (N,N,N′,N′-m-xylylenediamine tetraacetate) with H2O2 resulted in regioselective hydroxylation of the m-xylyl linker. The reaction mimics the self-hydroxylation of a phenylalanine side chain found for ribonucleotide reductase (R2-W48F/D84E).

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