New building blocks for the assembly of sequence selective molecular zippers
Literature Information
Chistopher A. Hunter, Philip S. Jones, Pascale M. N. Tiger, Salvador Tomas
Synthetic H-bonded molecular zippers contain no sequence information that can be used to engineer the selective binding interactions characteristic of biopolymers; reversing the sense of the amide bonds in the two binding partners generates a new orthogonal recognition motif and the mutually complementary binding partners form complexes an order of magnitude more stable than the corresponding mismatch complexes.
Related Literature
Conference report. European Winter Conference on Plasma Spectrochemistry: January 8–14th, 1989, Reutte, Tyrol, Austria
DOI: 10.1039/JA989040479C
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