Nonenzymatic peptide-based catalytic asymmetric phosphorylation of inositol derivatives

Literature Information

Publication Date 2003-06-24
DOI 10.1039/B304015C
Impact Factor 6.222
Authors

Bianca R. Sculimbrene, Adam J. Morgan, Scott J. Miller


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Abstract

The ability to use small peptides as catalysts for asymmetric phosphorylation provides opportunities for rapid syntheses of phosphate-containing compounds and natural products. This short review outlines the genesis of this concept and its reduction to practice in the context of concise syntheses of the enantiomeric D-I-1P and D-I-3P targets. The implications for the development of additional site-selective catalysts are discussed.

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