Compound Q&A

How is 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3) typically synthesized?

Answer

4-Methyl-6-(trifluoromethyl)quinoline
4-Methyl-6-(trifluoromethyl)quinoline is typically synthesized via the reaction of 4-chloro-6-(trifluoromethyl)quinoline with methylamine. The reaction is catalyzed by a base such as potassium carbonate. The yield is generally high, and selectivity towards the desired product is excellent.

About

CAS No 40716-16-3
English Name 4-Methyl-6-(trifluoromethyl)quinoline
Molecular Formula C11H8F3N
Molecular Weight 211.18599999999995 g/mol
SMILES FC(C1=CC=C2N=CC=C(C)C2=C1)(F)F
InChIKey TZZYMAHXPPUHML-UHFFFAOYSA-N
Last Updated: 2026-03-31 22:55

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