A tuning fork-shaped bisbenzothiazole derivative as a pH-responsive digital fluorescent probe and its ex vivo evaluation

Literature Information

Publication Date 2023-11-20
DOI 10.1039/D3AY01702H
Impact Factor 2.896
Authors

Priya Ranjan Sahoo, Nikhil Kumar, Keloth Sairam, L. K. Gulati, G. K. Gulati, Anupama Datta, Satish Kumar


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Abstract

A new highly emissive pH-responsive near-IR active digital probe was designed and synthesized. The probe is based on a bisbenzothiazole motif with a highly vulnerable hydrogen unit attached in an intramolecular fashion. The probe produced a large Stokes shift which was observed to be highly pH dependent. The optical pH dependence can be used for sensing pH over a wide range.

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Analytical Methods

Analytical Methods
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Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development

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