A novel copper-based nanozyme: fabrication and application for colorimetric detection of resveratrol

Literature Information

Publication Date 2023-11-13
DOI 10.1039/D3AY01666H
Impact Factor 2.896
Authors

Wanxin Li, Jiaxin Sun, Yao Xin, Yu Han, Yanyang Sun, Aijun Li, Zhi Wang


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Abstract

A novel nanozyme (urea@Cu-NF) was synthesized by self-assembly of urea and copper phosphate with urea as plasticizer. Urea@Cu-NF exhibited excellent peroxidase-like activity with the ability to oxidize TMB in the presence of H2O2. However, its peroxidase-like activity could be inhibited by resveratrol, leading to an absorption decrease in the intensity of oxTMB. Based on this phenomenon, a colorimetric method was designed for resveratrol detection. The colorimetric reaction could be completed within 20 min with a linear range of 1–120 μM. The limit of detection (LOD) of resveratrol is 0.43 μM. Our experimental results demonstrate that urea@Cu-NF has enormous potential to function as a cheap and accurate quality detection tool.

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Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development

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