Divergent synthesis of hydropyridine derivatives via nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclizations

Literature Information

Publication Date 2017-08-16
DOI 10.1039/C7QO00596B
Impact Factor 5.281
Authors

Hongxing Jin, Erqing Li


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Abstract

A nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclization strategy between allenic esters and α,β-unsaturated ketimines was discovered, affording a series of hydropyridine derivatives in moderate to good yields under mild conditions.

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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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