Catalytic asymmetric synthesis of hetero-substituted oxindoles
Literature Information
Publication Date
2017-07-05
DOI
10.1039/C7QO00446J
Impact Factor
5.281
Authors
View Original
Abstract
Chiral disubstituted oxindoles represent an important family of bioactive molecules. The construction of asymmetric quaternary carbon in the cyclopentane ring is therefore a challenging problem for organic chemists. In the last few years, many papers have appeared on asymmetric catalytic methods for the synthesis of these compounds and the literature on spirocyclic derivatives, 3-substituted-3-hydroxyoxindoles and 3-substituted-3-aminooxindoles has been largely reviewed. The literature on other hetero-substituted oxindoles has not been fully reviewed after 2011. This review aims to fill this gap by covering the literature on these topics until the end of 2016. A special section is also devoted to indoline-thiones.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
cis-3-Amino-1-(trifluoromethyl)cyclobutanol hydrochloride (1:1)
CAS Number:
1408075-16-0
Molecular Formula:
C5H9ClF3NO
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