cis-3-Amino-1-(trifluoromethyl)cyclobutanol hydrochloride (1:1)
CAS Number:
1408075-16-0
Molecular Formula:
C5H9ClF3NO
A one-pot, metal-free approach to bicyclic 2-pyridones
Literature Information
Publication Date
2017-07-03
DOI
10.1039/C7QO00406K
Impact Factor
5.281
Authors
Wannaporn Disadee
View Original
Abstract
A one-pot, metal-free approach for the synthesis of 3,4-disubstituted, bicyclic 2-pyridones was developed. The reaction occurred through the intramolecular, two-fold sequential cyclization of Michael adducts under thermal basic conditions. The methodology proceeded with a range of substrates to afford bicyclic 2-pyridones in up to 85% yield, and provided direct and easy access to two Tylophora alkaloid core structures.
Related Literature
NO2 quantum yields from ultraviolet photodissociation of methyl and isopropyl nitrate
Paula Gorrotxategi Carbajo, Andrew J. Orr-Ewing
2010-04-20
Paper
DOI: 10.1039/C001425G
A theoretical study of the hydrogen bond donor capability and co-operative effects in the hydrogen bond complexes of the diaza-aromatic betacarbolines
Antonio Sánchez-Coronilla, Manuel Balón, Enrique Sánchez Marcos, María A. Muñoz, Carmen Carmona
2010-03-26
Paper
DOI: 10.1039/B923284B
Matrix isolation studies on the co-condensation reactions of molecular SiO and GeO: the characterisation of the novel cyclic species SiGeO2, Si2GeO3 and SiGe2O3
J. Steven Ogden, David C. Harrowven, Robert S. Wyatt, Francesco Ferrante, John P. Cannady
2010-04-22
Paper
DOI: 10.1039/C001453B
Influence of binder properties on kinetic and transport processes in polymer electrolyte fuelcellelectrodes
Satheesh Sambandam, Vijay Ramani
2010-04-09
Paper
DOI: 10.1039/B921916A
Ab initio static and molecular dynamics study of the absorption spectra of the 4-styrylpyridine photoswitch in its cis and trans forms
Latévi Max Lawson Daku, Jorge Linares, Marie-Laure Boillot
2010-04-13
Paper
DOI: 10.1039/B920850J
A novel method to measure diffusion coefficients in porous metal–organic frameworks
Olexandra Zybaylo, Osama Shekhah, Hui Wang, Maxim Tafipolsky, Rochus Schmid, Diethelm Johannsmann, Christof Wöll
2010-06-07
Paper
DOI: 10.1039/B927601G
Photostability and solvation: photodynamics of microsolvated zwitterionic glycine
2010-02-11
Paper
DOI: 10.1039/B925246K
Stepwise in situ synthesis and characterization of metallophthalocyanines@mesoporous matrix SBA-15 composites
Jiangtian Li, Limin Guo, Jianlin Shi
2010-03-26
Paper
DOI: 10.1039/B925431E
Fusion and alloying of (bi)metallic nanocrystals onto TiO2nanowires in the presence of surface grafted polymer brushes
Haiyuan Hu, Bo Yu, Xiaolong Wang, Shaobai Li, Feng Zhou
2010-03-31
Paper
DOI: 10.1039/B925002F
The UV absorption of nucleobases: semi-classical ab initiospectra simulations
Mario Barbatti
2010-03-29
Paper
DOI: 10.1039/B924956G
You might also like
Compound Q&A
What precautions should be taken when handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3)?
When handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3), safety go...
40716-16-34-Methyl-6-(trifluor...
Compound Q&A
What is 4-(3,5-Difluorophenyl)aniline (CAS: 405058-00-6)?
4-(3,5-Difluorophenyl)aniline is an aromatic organic compound with the CAS numbe...
405058-00-64-(3,5-Difluoropheny...
Compound Q&A
How is 5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid (CAS: 338982-07-3) typically synthesized?
5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid can ...
338982-07-35-{[4-(Trifluorometh...
Compound Q&A
What is the market or research trend for 4-Benzylaniline hydrochloride (CAS: 6317-57-3)?
The market for 4-Benzylaniline hydrochloride (CAS: 6317-57-3) is steadily growin...
6317-57-34-Benzylaniline hydr...
Compound Q&A
Is [3-(Diethylsulfamoyl)phenyl]boronic acid (CAS: 871329-58-7) safe?
[3-(Diethylsulfamoyl)phenyl]boronic acid is generally considered safe when handl...
871329-58-7[3-(Diethylsulfamoyl...
Compound Q&A
What are the main uses of 3-Bromo-2,5-dimethoxyaniline (CAS: 115929-62-9)?
3-Bromo-2,5-dimethoxyaniline is mainly used in the pharmaceutical and chemical i...
115929-62-93-Bromo-2,5-dimethox...
Compound Q&A
What regulatory guidelines apply to N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7)?
N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7) is subject to ...
915922-67-7N-Methyl-1-(5-methyl...
Compound Q&A
What industries use Carbamic acid, N-[(5S)-5,6-diamino-6-oxohexyl]-, 1,1-dimethylethyl ester (CAS: 24828-96-4)?
This compound is primarily used in the pharmaceutical industry for the synthesis...
24828-96-4Carbamic acid, N-[(5...
Compound Q&A
How should 2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) be stored?
2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) sho...
1298101-47-92-Methyl-2-propanyl ...
Compound Q&A
What industries use Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9)?
Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9) is utilized in the pharma...
367-33-9Ethyl 2-bromo-4,4,4-...
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-15-[(2R,3S)-3-benzamido-3-phenyl-2-(2,2,2-trichloroethoxycarbonyloxy)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate structure](https://static.chemtradehub.com/structs/100/100431-55-8-7104.webp "[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-15-[(2R,3S)-3-benzamido-3-phenyl-2-(2,2,2-trichloroethoxycarbonyloxy)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate structure")
![N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide structure](https://static.chemtradehub.com/structs/109/109032-22-6-7c88.webp "N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide structure")
N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide
CAS Number:
109032-22-6
Molecular Formula:
C13H12N2O6S
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.