Iodine-catalyzed cascade annulation of alkynes with sodium arylsulfinates: assembly of 3-sulfenylcoumarin and 3-sulfenylquinolinone derivatives
Literature Information
Yanni An, Jianxiao Li, Shaorong Yang, Zhongzhi Zhu, Huanfeng Jiang
An efficient and versatile iodine-catalyzed electrophilic cyclization has been achieved to afford functionalized 3-sulfenylcoumarin and 3-sulfenylquinolinone derivatives in moderate to good yields from readily available alkynes with sodium arylsulfinates. Moreover, broad substrate scope, excellent functional group compatibility, and high-value products make this protocol practical and attractive, offering potential applications in organic synthesis and medicinal chemistry.
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