Copper-catalyzed oxidative dehydrogenative coupling of carboxylic acids with H-phosphonates: an efficient and practical approach to acyl phosphate esters

Literature Information

Publication Date 2017-06-05
DOI 10.1039/C7QO00298J
Impact Factor 5.281
Authors

Hong Fu, Tao Yang, Jia-Qi Shang, Jia-Li Zhou, Meng Sun, Ya-Min Li


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Abstract

A copper-catalyzed oxidative dehydrogenative coupling of carboxylic acids with H-phosphonates is developed. This transformation exhibits a wide substrate scope and good functional group tolerance, providing a straightforward and highly efficient access to acyl phosphate esters. A possible mechanism for the reaction is proposed.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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