Phase behavior of lysozyme solutions in the liquid–liquid phase coexistence region at high hydrostatic pressures

Literature Information

Publication Date 2016-05-05
DOI 10.1039/C6CP01791F
Impact Factor 3.676
Authors

Julian Schulze, Johannes Möller, Jonathan Weine, Karin Julius, Nico König, Julia Nase, Michael Paulus, Metin Tolan, Roland Winter


View Original

Abstract

We present results from small-angle X-ray scattering and turbidity measurements on the effect of high hydrostatic pressure on the phase behavior of dense lysozyme solutions in the liquid–liquid phase separation region, and characterize the underlying intermolecular protein–protein interactions as a function of temperature and pressure under charge-screening conditions (0.5 M NaCl). A reentrant liquid–liquid phase separation region is observed at elevated pressures, which may originate in the pressure dependence of the solvent-mediated protein–protein interaction. A temperature-pressure-concentration phase diagram was constructed for highly concentrated lysozyme solutions over a wide range of temperatures, pressures and protein concentrations including the critical region of the liquid–liquid miscibility gap.

Related Literature

Theoretical predication of the high hydrogen evolution catalytic activity for the cubic and tetragonal SnP systems

Jingwei Liu, Guangtao Yu, Ran Zhang, Xuri Huang, Wei Chen

2019-02-08 Paper

DOI: 10.1039/C9CP00618D

Bayesian determination of the effect of a deep eutectic solvent on the structure of lipid monolayers

Karen J. Edler, Stephen C. Parker

2019-02-22 Paper

DOI: 10.1039/C9CP00203K

Inside front cover

Cover

DOI: 10.1039/C9CP90089F

Assessing relative humidity dependent photoacoustics to retrieve mass accommodation coefficients of single optically trapped aerosol particles

Matus E. Diveky, Sandra Roy, Johannes W. Cremer, Grégory David, Ruth Signorell

2018-12-13 Paper

DOI: 10.1039/C8CP06980H

Computational microscopy study of the granular structure and pH dependence of PEDOT:PSS

Mohsen Modarresi, Igor Zozoulenko

2019-03-04 Paper

DOI: 10.1039/C8CP07141A

Structural studies of spray pyrolysis synthesized oxygen deficient anatase TiO2 thin films by using X-ray absorption spectroscopy

Madhusmita Sahoo, A. K. Yadav, Subrata Ghosh, S. N. Jha, D. Bhattacharyya, Tom Mathews

2019-02-18 Paper

DOI: 10.1039/C8CP06811A

Tuning of the gold work function by carborane films studied using density functional theory

Martin Hladík, Aliaksei Vetushka, Antonín Fejfar, Héctor Vázquez

2019-02-22 Paper

DOI: 10.1039/C9CP00346K

Shape-selective synthesis of nanoceria for degradation of paraoxon as a chemical warfare simulant

Greta Camilla Magnano, Marie Alexandrine Bolzinger, Lucian Roiban, Frédéric Chaput, Isabelle Pitault, Stéphanie Briançon, Thierry Devers, Karine Masenelli-Varlot, Matthieu Bugnet, David Amans

2019-02-15 Paper

DOI: 10.1039/C9CP00179D

Evaluation of spin-flip scattering in chirality-induced spin selectivity using the Riccati equation

Daniel Nürenberg, Helmut Zacharias

2019-01-22 Paper

DOI: 10.1039/C8CP07257D

You might also like

Compound Q&A

What are the main uses of 4-Nitrophenyl phosphate disodium salt hexahydrate (CAS: 333338-18-4)?

4-Nitrophenyl phosphate disodium salt hexahydrate is primarily used as a substra...

333338-18-44-Nitrophenyl phosph...
Compound Q&A

What are the main uses of 2-(Trifluoromethyl)-1,3-oxazole-4-carboxylic Acid (CAS: 1060816-01-4)?

2-(Trifluoromethyl)-1,3-oxazole-4-carboxylic Acid (CAS: 1060816-01-4) is widely ...

1060816-01-42-(Trifluoromethyl)-...
Compound Q&A

How should 2-Fluoro-4-biphenylcarboxylic acid (CAS: 137045-30-8) be stored?

2-Fluoro-4-biphenylcarboxylic acid should be stored in a cool, dry place at room...

137045-30-82-Fluoro-4-biphenylc...
Compound Q&A

What industries use Prednisolone-21-Carboxylic Acid (CAS: 61549-70-0)?

Prednisolone-21-Carboxylic Acid is primarily used in the pharmaceutical industry...

61549-70-0Prednisolone-21-Carb...
Compound Q&A

How should 4-(Hydrazinomethyl)-1,2,3-benzenetriol (CAS: 3614-72-0) be stored?

4-(Hydrazinomethyl)-1,2,3-benzenetriol (CAS: 3614-72-0) should be stored in a co...

3614-72-04-(Hydrazinomethyl)-...
Compound Q&A

What industries use 4-Amino-1-methyl-1H-pyrazole-5-carboxylic acid hydrochloride (CAS: 92534-70-8)?

4-Amino-1-methyl-1H-pyrazole-5-carboxylic acid hydrochloride (CAS: 92534-70-8) i...

92534-70-84-Amino-1-methyl-1H-...
Compound Q&A

What regulatory guidelines apply to dehydropachymic acid (CAS: 77012-31-8)?

Dehydropachymic acid (CAS: 77012-31-8) is regulated by various agencies. It fall...

77012-31-8Dehydropachymic acid
Compound Q&A

What is the market or research trend for 6-[(2,2-Dimethylpropanoyl)amino]nicotinic acid (CAS: 898561-66-5)?

The market and research trends for 6-[(2,2-Dimethylpropanoyl)amino]nicotinic aci...

898561-66-56-[(2,2-Dimethylprop...
Compound Q&A

How should 1,10-Phenanthroline-2,9-dicarbaldehyde (CAS: 57709-62-3) be stored?

1,10-Phenanthroline-2,9-dicarbaldehyde should be stored in a cool, dry place awa...

57709-62-31,10-Phenanthroline-...
Compound Q&A

How is 5-Carbamoyl-11-oxo-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate (CAS: 113952-21-9) typically synthesized?

5-Carbamoyl-11-oxo-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate can be synt...

113952-21-95-Carbamoyl-11-oxo-1...

Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.