An ultrasensitive electrochemical immunosensor based on the synergistic effect of quaternary Cu2SnZnS4 NCs and cyclodextrin-functionalized graphene
Literature Information
Lei Liu, Yihe Zhang, Ruifeng Du, Jinhong Li, Xuelian Yu
In this study, highly monodispersed Cu2SnZnS4 NCs with a quasi-spherical structure were prepared to construct a sandwich-type electrochemical immunosensor for alpha-fetoprotein detection. Quaternary Cu2SnZnS4 NCs as novel biomimetic catalysts show an efficient intrinsic peroxidase-like activity for H2O2 reduction. This excellent catalytic activity is ascribed to the higher electroconductivity than those of the binary Cu2S and ternary Cu2SnS3 NCs. Moreover, β-cyclodextrin-functionalized graphene sheets are used as substrate materials that can capture large amounts of primary antibodies due to host–guest interaction and high surface area. Under the optimized conditions, the electrochemical immunosensor exhibites a wide working range from 0.5 pg mL−1 to 10 ng mL−1 and a detection limit of 0.16 pg mL−1 at a signal-to-noise ratio of 3. Good sensitivity, reproducibility, and stability demonstrate its potential application in clinical diagnostics.
Recommended Journals
Related Literature
A graphene–Mo2C heterostructure for a highly responsive broadband photodetector
Xiaozhi Bao, Tian Sun, Yan Liu, Chuan Xu, Weiliang Ma, Junpo Guo, Yun Zheng, Shivananju Bannur Nanjunda, Huating Liu, Zongyu Huang, Shenghuang Lin, Guichuan Xing, Wencai Ren, Qiaoliang Bao, Huaiyu Shao
DOI: 10.1039/D1CP03536C
Sequence-dependent aggregation-prone conformations of islet amyloid polypeptide
Bumjoon Choi, Nam Hyeong Kim, Geun Young Jin, Yung Sam Kim, Kilho Eom
DOI: 10.1039/D1CP01061A
Local structure and NO adsorption/desorption property of Pd2+ cations at different paired Al sites in CHA zeolite
Shunsaku Yasumura, Taihei Ueda, Hajime Ide, Katsumasa Otsubo, Chong Liu, Nao Tsunoji, Zen Maeno
DOI: 10.1039/D1CP02668B
Aggregation-induced negative differential resistance in graphene oxide quantum dots
Sonia Sharma, Chieh-An Cheng, Svette Reina Merden Santiago, Denice N. Feria, Chi-Tsu Yuan, Sheng-Hsiung Chang, Tai-Yuan Lin, Ji-Lin Shen
DOI: 10.1039/D1CP01529J
The effect of interface angle on the thermal conductivity of Si/Ge superlattices
Aleksandr Chernatynskiy, Xiao-Feng Zhao
DOI: 10.1039/D1CP03544D
Kinetic and thermodynamic stability comparison for the fibrillar form of small amyloid-β(1–42) oligomers using scaled molecular dynamics
Debasis Saha, Biman Jana
DOI: 10.1039/D1CP01866C
The role of halogen bonding in metal free phosphors
Ramin Ansari, Daniel Hashemi, John Kieffer
DOI: 10.1039/D1CP01325D
New complexes of liquid crystal discotic triphenylenes: induction of the double gyroid phase
O. A. Otmakhova, G. N. Bondarenko, G. A. Shandryuk, A. S. Merekalov, R. V. Talroze
DOI: 10.1039/D1CP00660F
Deformation mechanism of a metal–organic framework glass under indentation
Theany To, Malwina Stepniewska, Haizheng Tao, Laurent Calvez, Xianghua Zhang, Morten M. Smedskjaer, Yuanzheng Yue
DOI: 10.1039/D1CP02213J
Single sheets of graphene for fabrication of fibers with enhanced mechanical properties
Muhammad G. Salim, Luke A. Thimons, Min A. Kim, Brennan Carr, Michelle Montgomery, Nathan Tolman, Tevis D. B. Jacobs, Haitao Liu
DOI: 10.1039/D1CP03238K
You might also like
What precautions should be taken when handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3)?
When handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3), safety go...
What is 4-(3,5-Difluorophenyl)aniline (CAS: 405058-00-6)?
4-(3,5-Difluorophenyl)aniline is an aromatic organic compound with the CAS numbe...
How is 5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid (CAS: 338982-07-3) typically synthesized?
5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid can ...
What is the market or research trend for 4-Benzylaniline hydrochloride (CAS: 6317-57-3)?
The market for 4-Benzylaniline hydrochloride (CAS: 6317-57-3) is steadily growin...
Is [3-(Diethylsulfamoyl)phenyl]boronic acid (CAS: 871329-58-7) safe?
[3-(Diethylsulfamoyl)phenyl]boronic acid is generally considered safe when handl...
What are the main uses of 3-Bromo-2,5-dimethoxyaniline (CAS: 115929-62-9)?
3-Bromo-2,5-dimethoxyaniline is mainly used in the pharmaceutical and chemical i...
What regulatory guidelines apply to N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7)?
N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7) is subject to ...
What industries use Carbamic acid, N-[(5S)-5,6-diamino-6-oxohexyl]-, 1,1-dimethylethyl ester (CAS: 24828-96-4)?
This compound is primarily used in the pharmaceutical industry for the synthesis...
How should 2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) be stored?
2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) sho...
What industries use Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9)?
Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9) is utilized in the pharma...
Source Journal
Analyst

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.











![6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid structure 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid structure](https://static.chemtradehub.com/structs/136/1369160-12-2-6524.webp)


