Colorimetric detection of biological hydrogen sulfide using fluorosurfactant functionalized gold nanorods

Literature Information

Publication Date 2015-09-17
DOI 10.1039/C5AN01665G
Impact Factor 4.616
Authors

Xuan Zhang, Wenjuan Zhou, Zhiqin Yuan, Chao Lu


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Abstract

As a well-known environmental pollutant but also an important gaseous transmitter, the specific detection of hydrogen sulfide (H2S) is significant in biological systems. In this study, fluorosurfactant functionalized gold nanorods (FSN-AuNRs) have been proposed to act as selective colorimetric nanoprobes for H2S. With the combination of strong gold–S interactions and small FSN bilayer interstices, FSN-AuNRs demonstrate favorable selectivity and sensitivity toward H2S over other anions and small biological molecules. The practical application of the present method in biological H2S detection was validated with human and mouse serum samples. Moreover, the proposed nanoprobe can also be used for evaluating the activity of H2S synthetase.

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