Silver nanostructures in laser desorption/ionization mass spectrometry and mass spectrometry imaging

Literature Information

Publication Date 2015-07-27
DOI 10.1039/C5AN00943J
Impact Factor 4.616
Authors

Justyna Sekuła, Joanna Nizioł, Wojciech Rode, Tomasz Ruman


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Abstract

Silver nanoparticles have been successfully applied as a matrix replacement for the laser desorption/ionization time-of-flight mass spectrometry (LDI-ToF-MS). Nanoparticles, producing spectra with highly reduced chemical background in the low m/z region, are perfectly suited for low-molecular weight compound analysis and imaging. Silver nanoparticles (AgNPs) can efficiently absorb ultraviolet laser radiation, transfer energy to the analyte and promote analyte desorption, but also constitute a source of silver ions suitable for analyte cationisation. This review provides an overview of the literature on silver nanomaterials as non-conventional desorption and ionization promoters in LDI-MS and mass spectrometry imaging.

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Contents list

Front/Back Matter

DOI: 10.1039/C7QO90039B

Back cover

Cover

DOI: 10.1039/C8QO90018C

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