Analysis of mass-limited mixtures using supercritical-fluid chromatography and microcoil NMR

Literature Information

Publication Date 2015-07-27
DOI 10.1039/C5AN00772K
Impact Factor 4.616
Authors

Michael C. D. Tayler, S. (Bas) G. J. van Meerten, Arno P. M. Kentgens, P. Jan M. van Bentum


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Abstract

A protocol is presented for offline microfluidic NMR analysis hyphenated with supercritical chromatographic separation. The method demonstrates quantitative detection with good sensitivity. Typical sample amounts of 10 nanomoles can be detected in a fast and cost-effective manner.

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