Growing polymers from peptides and proteins: a biomedical perspective
Literature Information
Publication Date
2013-10-11
DOI
10.1039/C3PY01089A
Impact Factor
5.582
Authors
Yizhi Qi
View Original
Abstract
This review covers the development of the in situ growth of polymers from biomolecules, also termed the “grafting from” conjugation methodology. We trace the evolution of this field of research, with an emphasis on recently developed methods to synthesize polymer conjugates of peptides and proteins with control over the site of conjugation, the stoichiometry of the conjugate, and the chain length and polydispersity of the polymer. We highlight the functional properties and potential biomedical applications of the peptide/protein–polymer conjugates, including conjugates with more advanced architecture and self-assembly behaviour.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
6-CHLORO-2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALINE, 97
CAS Number:
169-14-2
Molecular Formula:
C8H5ClN2O2
![(3R,5R)-1-[(Benzyloxy)carbonyl]-5-methyl-3-piperidinecarboxylic acid structure](https://static.chemtradehub.com/structs/126/1269757-29-0-c552.webp "(3R,5R)-1-[(Benzyloxy)carbonyl]-5-methyl-3-piperidinecarboxylic acid structure")
(3R,5R)-1-[(Benzyloxy)carbonyl]-5-methyl-3-piperidinecarboxylic acid
CAS Number:
1269757-29-0
Molecular Formula:
C15H19NO4
cis-3-Amino-1-(trifluoromethyl)cyclobutanol hydrochloride (1:1)
CAS Number:
1408075-16-0
Molecular Formula:
C5H9ClF3NO
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