Dielectric measurements of aqueous DNA solutions up to 110 GHz

Literature Information

Publication Date 2014-04-23
DOI 10.1039/C3CP55272A
Impact Factor 3.676
Authors

Elena Ermilova, Frank F. Bier, Ralph Hölzel


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Abstract

A measurement system for broadband dielectric spectroscopy of biological samples for frequencies between 25 MHz and 110 GHz is presented. It is based on a vector network analyzer and a 1.19 mm-diameter open-ended coaxial probe. Complex reflection coefficients of aqueous Na–DNA solutions are measured in the frequency domain at a constant temperature of 25 °C. Complex permittivity spectra are analysed at various solute concentrations and two dispersions are observed. The first one is located at about 19 GHz and is due to the reorientation of water molecules. The second one is located at approximately 100 MHz and is interpreted as being caused by DNA counterion fluctuations. The relaxation frequency of free water in solutions appears to be practically unaffected by the presence of DNA. For the relaxation in the MHz region the dielectric loss maximum shifts to higher frequencies and the distribution of relaxation times becomes broader with increasing polymer concentration.

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Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
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Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

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